The codeine in acetaminophen and codeine phosphate tablets may possibly increase the frequency of seizures in sufferers with seizure disorders, and will increase the risk of seizures taking place in other clinical configurations connected to seizures.

Clients ought to recognize that this drug, even when taken as advised can result in habit, abuse, and misuse; instruct clients not to share their drug with Other people and protect their drug from theft or misuse.

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Take this medication by mouth as directed by your health care provider. Chances are you'll choose this drug with or with out meals. If you have nausea, it could help to just take this drug with foods.

Hepatotoxicity Acetaminophen has long been connected to situations of acute liver failure, at times resulting in liver transplant and death.

Other considerably less routinely observed adverse reactions predicted from opioid analgesics, which includes acetaminophen and codeine phosphate tablets:

Due to the hazards of habit, abuse and misuse, the bottom dose with the shortest period consistent with unique patient treatment objectives needs to be employed.

If prolonged opioid use is necessary in a pregnant girl, the affected person should be suggested of the potential risk of neonatal opioid withdrawal syndrome and make sure acceptable cure will probably be offered.

Soon after halting a CYP3A4 inhibitor, as the effects on the inhibitor drop, it may well bring about decreased codeine levels, larger norcodeine concentrations, and less metabolism through CYP2D6 with resultant lessen morphine ranges (see CLINICAL PHARMACOLOGY), leading to diminished opioid efficacy or maybe get more info a withdrawal syndrome in sufferers who had designed Bodily dependence to codeine.

Tell clients and caregivers not to increase opioid dosage without to start with consulting a clinician. Suggest individuals to hunt professional medical consideration when website they knowledge signs of hyperalgesia, such as worsening discomfort, elevated sensitivity to ache, or new discomfort (see WARNINGS; website ADVERSE REACTIONS).

Chance of Medication Problems: Guarantee accuracy when get more info prescribing, dispensing, and administering the oral Remedy; dosing mistakes click here due to confusion concerning mg and mL, together with other codeine solutions of various concentrations may lead to accidental overdose and Loss of life.

Instruct patients to discontinue acetaminophen and codeine phosphate tablets straight away and look for professional medical treatment if they working experience these indicators. Do not prescribe acetaminophen and codeine phosphate tablets for clients with acetaminophen allergy (see PRECAUTIONS, Data for People/Caregivers).

Usually do not give acetaminophen and codeine phosphate tablets to a youngster younger than 18 several years of age just after surgical procedure to get rid of the tonsils and/or adenoids.

Accidental ingestion of acetaminophen and codeine phosphate tablets, Specially by youngsters, may end up in respiratory despair and Loss of life on account of an overdose of codeine.